148
Biophysical Society 58
th
Annual Meeting, San Francisco, California
2757-P
os
B
oard
#B449
EXTRACELLULAR CONTRIBUTIONS TO ALCOHOL
MODULATION OF PENTAMERIC LIGAND-GATED ION
CHANNELS.
Amber Plante
2758-P
os
B
oard
#B450
ACTIVATION MECHANISM OF ELIC BY PROPYLAMINE.
Alessandro Marabelli, Remigijus Lape,
Lucia Sivilotti
2759-P
os
B
oard
#B451
PROKARYOTIC CYS-LOOP RECEPTOR HOMOLOGS AS
MECHANISTIC MODELS FOR CHANNEL FUNCTION.
Matthew Rienzo
, Oliver S. Shafaat, Harry B. Gray, Sarah C. R. Lummis,
Dennis A. Dougherty
2760-P
os
B
oard
#B452
BIOCHEMICAL AND FUNCTIONAL CHARACTERIZATION
OF A NOVEL PROKARYOTE LIGAND-GATED ION CHANNEL
CLIC.
Mieke Nys
, Radovan Spurny, Zander Claes, Chris Ulens
2761-P
os
B
oard
#B453
UTILIZING NON-EQUILIBRIUM METHODS TO PROBE THE
EFFECTS OF GENERAL ANESTHETICS ON LIGAND-GATED
ION CHANNEL DYNAMICS.
Mark J. Arcario
, Emad Tajkhorshid
2762-P
os
B
oard
#B454
LOOSE PACKING OF THE EXTRACELLULAR DOMAIN CORE
OF PENTAMERIC LIGAND-GATED ION CHANNELS IS
IMPORTANT FOR FAST ACTIVATION AND DESENSITIZATION.
Cosma D. Dellisanti
, Cynthia Czajkowski
2763-P
os
B
oard
#B455
CONSTRUCTION AND CHARACTERIZATION OF A
FUNCTIONAL GLIC-GABA
ρ
LIGAND-GATED ION CHANNEL
CHIMERA.
Borna Ghosh
, Varun Tiwari, Cynthia Czajkowski
2764-P
os
B
oard
#B456
ALLOSTERIC MODULATION OF GABA-A RECEPTORS BY
DIFFERENT DRUGS.
Borna Ghosh
, Tzu-Wei Tsao, Cynthia Czajkowski
2765-P
os
B
oard
#B457
MECHANISM OF INHIBITION OF RECOMBINANT GABAA
RECEPTORS BY PENTYLENETETRAZOLE AND ITS ALLEVIATION
BY ANTICONVULSANTS. Akimasa Iijima,
Yongli Chen
2766-P
os
B
oard
#B458
γ
-AMINOBUTYRIC ACID INDUCED CONFORMATIONAL
CHANGE IN GABAAR MEASURED BY PULSED ELECTRON
PARAMAGNETIC RESONANCE. Yinghui Zhang, Youssef Jounaidi,
Jessica L. Sarver, Xiaojuan Zhou, David S. Cafiso,
Keith W. Miller
2767-P
os
B
oard
#B459
MOLECULAR CLONING OF A GABA RECEPTOR SUBUNIT
FROM CRAYFISH AND VOLTAGE-CLAMP ANALYSIS OF HOMO-
OLIGOMERIC RECEPTOR EXPRESSED IN HEK CELLS.
Eric N.
Jiménez-Vázquez
, Juan M. Arias, Ubaldo García
2768-P
os
B
oard
#B460
CONTRIBUTION OF STRUCTURAL ELEMENTS TO ACTIVATION
AND ALLOSTERIC MODULATION IN AN ANIONIC
LIGAND-GATED ION CHANNEL.
Ozge Yoluk
, Erika A. Riederer,
Magnus Andersson, Goran Klement, James R. Trudell, Edward J. Bertac-
cini, Rebecca J. Howard, Erik Lindahl
2769-P
os
B
oard
#B461
INTERACTION OF THE GLYCINE RECEPTOR ALPHA 1
BINDING SITE WITH PARTIAL AGONISTS.
Timo Greiner
,
Elliot Hurdiss, Rilei Yu, Remigijus Lape, Philip C. Biggin, Lucia G. Sivilotti
2770-P
os
B
oard
#B462
TOWARDS UNDERSTANDINGTHE INTERACTION OF AGONISTS
WITH THE HUMAN ALPHA1 GLYCINE RECEPTOR.
Rilei Yu
2771-P
os
B
oard
#B463
TOWARDS STRUCTURAL AND FUNCTIONAL DETERMI-
NATION OF A NON-DESENSITIZING
α
1 GLYCINE RECEP-
TOR.
Rathna J. Veeramachaneni
, Chelsee Donelan, Michael Cascio
2772-P
os
B
oard
#B464
METHODS FOR IDENTIFICATION OF STATE-DEPENDENT
CROSSLINKS FOR STRUCTURAL DETERMINATION OF MEM-
BRANE PROTEINS.
Chelsee A. Donelan
, Rathna Veeramachaneni,
Andrew Davic, Michael Cascio
Ion Channels and Disease I
(Boards #B465–#B493)
2773-P
os
B
oard
#B465
LEARNING THE KINETICS OF AMYLOID
β
PORE IN
ALZHEIMER’S DISEASE PATHOLOGY.
Ghanim Ullah
,
Angelo Demuro, Ian Parker, John E. Pearson
2774-P
os
B
oard
#B466
INVESTIGATING HOW A
β
AND
α
SYNUCLEIN OLIGOMERS
INITIALLY DEMAGE NEURONAL CELLS.
Anna Drews
2775-P
os
B
oard
#B467
ACUTE EFFECTS OF
β
-AMYLOID (1-42) OLIGOMERS ON RAT
PYRAMIDAL ENTORHINAL NEURONS. Miguel Cuaxospa,
Rosana Fiorentino,
Ubaldo Garcia
2776-P
os
B
oard
#B468
DISREGULATION OF CALCIUM HOMEOSTASIS CONNECTED
WITH FAMILIAL ALZHEIMER’S DISEASE.
Maria Ryazantseva
,
Ksenia Skobeleva, Elena Kaznacheyeva
2777-P
os
B
oard
#B469
TAU PROTEIN FORMS ION CHANNELS. Rustam Azimov,
Bruce L. Kagan
2778-P
os
B
oard
#B470
education
travel
awardee
ALTERATIONS IN IONIC CURRENTS AND GAP JUNCTIONAL
COUPLING BY PAN-HISTONE DEACETYLASE INHIBITION.
Dakshesh Patel
2779-P
os
B
oard
#B471
SELF-ASSEMBLY OF THE VIRAL CHANNEL FORMING PROTEIN
VPU OF HIV-1 USING COARSE-GRAINING MOLECULAR
DYNAMICS SIMULATIONS.
Meng-Han Lin
, Wolfgang B. Fischer
2780-P
os
B
oard
#B472
ION-TRAPPING IN HCV P7 HEXAMERIC BUNDLES -
A MOLECULAR DYNAMICS SIMULATION STUDY.
Wolfgang B. Fischer
, Yi-Ting Wang
2781-P
os
B
oard
#B473
STRUCTURE AND INHIBITION OF THE M2 PROTON
CHANNEL FROM THE INFLUENZA A VIRUS.
Jun Wang
,
Yibing Wu, William F. DeGrado
2782-P
os
B
oard
#B474
MECHANO-SENSITIVE ION CHANNELS (MSCS) PROVIDE
HUMAN BREAST CANCER CELLS WITH A SENSORIUM FOR
MECHANICAL STRESS.
Chouyang Li
, Simin Rezania,
Sarah Kammerer, Astrid Gorischek, Thomas Bauernhofer,
Wolfgang Schreibmayer
