149
Biophysical Society 58
th
Annual Meeting, San Francisco, California
T
U
E
S
D
A
Y
2783-P
os
B
oard
#B475
DIMINAZENE INTERACTION WITH ASIC1A CHANNELS.
Bogdan P. Amuzescu
, Thomas Knott, Olaf Scheel, Dan Mihailescu,
Maria Mernea
2784-P
os
B
oard
#B476
EFFECTS OF DISEASE-ASSOCIATED MUTATIONS ON THE
CONFORMATIONS OF GABA(A) RECEPTORS.
Sruthi Murlidaran
,
Reza Salari, Grace Brannigan
2785-P
os
B
oard
#B477
PROTEIN KINASE C-THETA CONTROLS THE CLC-1
CHLORIDE CHANNEL FUNCTION AND SKELETAL MUSCLE
PHENOTYPE: A BIOPHYSICAL AND GENE EXPRESSION STUDY
IN PKC-THETA NULL MICE.
Giulia M. Camerino
, Michela De Bellis,
Maria Cannone, Antonella Liantonio, Kejla Musaraj, Jean-Francois Desaphy,
Luca Madaro, Marina Bouchè, Sabata Pierno
2786-P
os
B
oard
#B478
BLOCKING KCA1.1 CHANNELS INHIBITS THE PATHOGENIC
FEATURES OF FIBROBLAST-LIKE SYNOVIOCYTES AND TREATS
RAT MODELS OF RHEUMATOID ARTHRITIS. Mark R. Tanner,
Xueyou Hu, Redwan Huq, Teresina Laragione, Rajeev B. Tajhya,
Frank T. Horrigan, Percio S. Gulko,
Christine Beeton
2787-P
os
B
oard
#B479
THE FUNCTIONAL SWTICH IN POTASSIUM CHANNELS IN
MYOTONIC DYSTROPHY TYPE 1 IMPAIRS PROLIFERATION,
MIGRATION AND FUSION DURING MYOGENESIS.
Rajeev B. Tajhya
, Xueyou Hu, Mark R. Tanner, Lubov Timchenko,
Christine Beeton
2788-P
os
B
oard
#B480
ALTERED GATING OF KV1.3 CHANNELS OF T LYMPHOCYTES
IN SMITH-LEMLI-OPITZ SYNDROME.
Andras Balajthy
,
Sandor Somodi, Maria Peter, Zoltan Petho, Laszlo Vigh, Gyorgy Panyi,
Peter Hajdu
2789-P
os
B
oard
#B481
LOCALIZATION OF THE
PLASMODIUM FALCIPARUM
K
+
CHANNEL, PFKCH1.
Matias Martin
, Mark Luciani,
Anders Hay-Schmidt, Peter Ellekvist, Dan A. Klaerke
2790-P
os
B
oard
#B482
MALIGNANT LYMPHOBLASTS IN T CELL ACUTE
LYMPHOBLASTIC LEUKEMIA EXPRESS HIGH LEVELS OF
KV1.3.
Eva Groessinger
, Lukas Weiss, Mingyi Chen, Heike Wulff,
Richard Greil, Hubert Kerschbaum
2791-P
os
B
oard
#B483
MARGATOXIN IS A NONSELECTIVE INHIBITOR OF KV1.3
CHANNELS - A COMPREHENSIVE STUDY.
Adam Bartok
,
Agnes Toth, Peter Hajdu, Zoltan Varga, Gyorgy Panyi
2792-P
os
B
oard
#B484
MECHANISMS OF ATP-SENSITIVE POTASSIUM CHANNEL
OVERACTIVITY IN CANTU MUTANTS.
Paige Cooper
,
Monica Sala-Rabanal, Colin Nichols
2793-P
os
B
oard
#B485
TWO-PORE-DOMAIN TASK-1 POTASSIUM CHANNELS
MODULATE PANCREATIC ISLET GLUCAGON SECRETION.
Prasanna Dadi, Brooke Luo,
David Jacobson
2794-P
os
B
oard
#B486
CLONING OF EQUINE KCNH2 AND KCNQ1 AS THE BASIS
FOR DIAGNOSING LONG QT SYNDROME IN HORSES.
Philip J. Pedersen
, Jon B. Flak, Rikke Buhl, Dan A. Klaerke
2795-P
os
B
oard
#B487
cpow
travel
awardee
ISOGENIC SETS OF HUMAN PLURIPOTENT STEM CELLS AS
MODEL OF LQT2 SYNDROME.
Simona Casini
, Milena Bellin,
Richard P. Davis, Cristina D’ Aniello, Jessica Haas,
Dorien Ward-van Oostwaard, Leon G. J. Tertoolen,
Karl-Ludwig Laugwitz, Alessandra Moretti, Christine L. Mummery
2796-P
os
B
oard
#B488
DYNAMIC ACTION POTENTIAL CLAMP INVESTIGATION
OF PRO-ARRHYTHMIC RISK OF DRUGS BINDING TO HERG
POTASSIUM CHANNELS.
Stefan A. Mann
, Jamie I. Vandenberg
2797-P
os
B
oard
#B489
CA
2+
SENSITIVITY OF L-TYPE CALCIUM CHANNEL
INACTIVATION PROBED BY CA
2+
PHOTOUNCAGING—WIN-
DOW ONTO CALMODULINOPATHIES.
Worawan Limpitikul
,
David T. Yue
2798-P
os
B
oard
#B490
TRAFFICKING-DEFECTIVE KIR6.1 (KATP) MUTATIONS IN
SUDDEN INFANT DEATH SYNDROME.
Bi-Hua Tan
, Rou-Mu Hu,
Blaise Peterson, Sinisa Dovat, Michael J. Ackerman,
Jonathan C. Makielski, Chunhua Song
2799-P
os
B
oard
#B491
HUMAN INDUCED PLURIPOTENT STEM CELL DERIVED
CARDIOMYOCYTES (HIPS-CM’S): AN EXPRESSION MODEL
SYSTEM FOR INVESTIGATING CARDIAC CHANNELOPATHIES.
Ravi Vaidyanathan
, John Kyle, Deborah L. Capes, Timothy J. Kamp,
Craig T. January, Lee L. Eckhardt, Jonathan C. Makielski
2800-P
os
B
oard
#B492
INTERLEUKIN 1
Β
MODULATES THE VENTRICULAR L-TYPE
CALCIUM CURRENT THROUGH ROS SIGNALLING.
Nabil El Khoury
, Sophie Mathieu, Céline Fiset
2801-P
os
B
oard
#B493
A NOVEL NA
V
1.1 MUTATION L1613P ASSOCIATED WITH
FAMILIAL HEMIPLEGIC MIGRAINE.
Chunxiang Fan
,
Frank Lehmann-Horn, Karin Jurkat-Rott
Other Channels
(Boards #B494–#B526)
2802-P
os
B
oard
#B494
cpow
travel
awardee
A LACK OF SIGNIFICANT LIPID INTERACTIONS IN THE
OPEN STATE OF MSCS IMPLIES A JACK-IN-THE-BOX TYPE
CHANNEL GATING MECHANISM.
Hannah R. Malcolm
,
Paul Blount, Joshua A. Maurer
2803-P
os
B
oard
#B495
FOLLOWING THE GLOBAL STRUCTURAL CHANGES OF AN
ION CHANNEL DURING ITS GATING BY USING A NOVEL
MASS SPECTROMETRY APPROACH.
Duygu Yilmaz
,
Albert Konijnenberg, Helgi Ingólfsson, Anna Dimitrova,
Siewert J. Marrink, Frank Sobott, Armağan Koçer
2804-P
os
B
oard
#B496
THE RATE OF OSMOTIC SHOCK DETERMINES BACTERIAL
SURVIVAL.
Heun Jin Lee
, Maja Bialecka-Fornal, Rob Phillips
2805-P
os
B
oard
#B497
GATING MECHANISM OF MECHANOSENSITIVE ION
CHANNELS STUDIED BY CONTINUUM MECHANICS.
Navid Bavi, Takeshi Nomura, Qinghua Qin,
Boris Martinac
