Limited evidence for effectiveness of radiotherapy on
bone quality or fracture risk
Fracture -> postoperative RT
•
Townsend et al, IJROBP 1995
•
N= 64
•
53% vs. 11% (MV, P< 0.01) → function
Impending
•
Koswig et al, Strahlenther.Onc. 1999
•
N= 107
•
8 Gy SF vs. 30 Gy / 10 fr.
•
Higher dose -> more recalcification
Groenen et al, R&O 2016, Willeumier et al. R&O 2016