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Limited evidence for effectiveness of radiotherapy on

bone quality or fracture risk

Fracture -> postoperative RT

Townsend et al, IJROBP 1995

N= 64

53% vs. 11% (MV, P< 0.01) → function

Impending

Koswig et al, Strahlenther.Onc. 1999

N= 107

8 Gy SF vs. 30 Gy / 10 fr.

Higher dose -> more recalcification

Groenen et al, R&O 2016, Willeumier et al. R&O 2016