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(different from “anesthesia”)
is defined as a state of minimal / absent pain perception
in the face of a potent neuropathic or nociceptive pain stimulus
without
intentional
alteration in awareness.
Therapeutic goal = pain relief
-not sedation, amnesia or unconsciousness.
è
ketamine given in subanesthetic doses
Fine PG.
Low-dose ketamine in the management of opioid non responsive terminal cancer pain.
J Pain and Symptom Manage 1999; 17: 296 –300.
“total analgesia” for
refractory pain
More & better treatment…?