62 / 604
0
500
1000
1500
2000
2500
W-4
W-3
W-2
D-7
D-3 D-2 D-1
Mean OME dose (mg/day)
Time before daeth in weeks
< 60 mg OME/dag (N=156)
60 - 299 mg OME/dag (N=533)
300 - 599 mg OME/dag (N=156)
600 - 900 mg OME/dag (N=52)
> 900 mg OME/dag (N=82)
Morphine, early provided in the disease trajectory,
is not automatically leading to tolerance/addiction!!
PCU Leuven
N = 1088patients