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50

100

150

200

250

300

350

400

Bone mets

No bone mets

20 40 60 80 100 120 140 160 180

Days

n=28

n=5

n=25

n=8

Fentanyl in µg/h

Opioïd consumption in oncological palliative patients

with or without bone metastases

Fen-Bel 5 study (Leuven patients = 53)

20 40 60 80 100 120 140 160 180

200