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Radiation tolerance with 2 Gy fraction radiotherapy of the liver:

Dawson et al.

Int J Radiat Oncol Biol Phys 2002;53:810-821

0 10 20 30 40 50 60 70 80 90

Whole liver

SBRT

Dose-response of normal liver with radiotherapy

given in 3 fractions

100%

0%

Liver failure

Dose (Gy)

Volume effect

Risk of liver failure