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Unresectable CRLM Local treatment

Phase II study in unresectable colorectal liver–limited metastases

Randomised to systemic treatment alone (

standard arm

) or systemic

treatment plus local treatment by RFA +/- resection (

experimental arm -

CMT

)

Primary end point: 30-month OS rate higher than 38% in CMT arm

119 patients were randomized

CRLM - colorectal liver metastases

Ruers T, JNCI 2017