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ADT and cardiac disease
•
Prospective cohort study 7637 subjects, nearly 30% exposed to ADT
•
Multivariable analyses:
In men without preexisting CVD, ADT was
associated with an increased risk of heart failure
(adjusted HR=1.81
,
95% CI 1.40–2.32
)
•
Only among patients with
preexisting CVD
was elevated risks of
arrhythmia (adjusted HR=1.44
, 95% CI 1.02–2.01), and
conduction
disorder (adjusted HR=3.11
, 95% CI 1.22, 7.91) observed
Haque R, BJC 2017