1232 / 1578
/
• Pain response after conventional RT:
~70%
• Pain control after 3 – 6 months:
~35%
# patients Fractionation Complete or partial
pain response
Duration
Prince
1986
288
1 x 8Gy
10 x 3Gy
73%
64%
59% @ 3 mo
50% @ 3 mo
Gaze 1997
280
1 x 10Gy
5 x 4.5Gy
84%
89%
Median 3.5 mo
Median 3.5 mo
Steenland
1999
1171
1 x 8Gy
6 x 4Gy
72%
69%
Median 5 mo
Median 6 mo
Roos 2005
272
1 x 8Gy
5 x 4Gy
61%
53%
Median 3.5mo
Median 5.5 mo
Pain control with conventional radiotherapy
for bone metastases
ESTRO SBRT 2017 - Matthias Guckenberger
5
07.09.17
/
• Favorable OS in selected patients
• Contribution of SBRT?
OS in patients with vertebral metastases
Guckenberger submitted
Conventional radiotherapy
SBRT
Leithner Eur Spine J
ESTRO SBRT 2017 - Matthias Guckenberger
6
07.09.17