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• Conventional „low-dose“ radiotherapy with 1 x 8Gy is the
guideline recommended treatment of choice for painful
vertebral metastases
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Nevertheless:
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Lack of any response in 1 / 3 of the patients
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Incomplete pain reponse in 2 / 3 of the patients
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Limited palliative effect after 3 – 6 months
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Limited efficacy in mass-like metastases
Summary of conventional RT
ESTRO SBRT 2017 - Matthias Guckenberger
11
07.09.17
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Motivation to explore SBRT for
vertebral metastases
• Oligo-metastasis
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Improve OS
• Oligo-progression
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Delay of systemic treatment
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Delay change of systemic treatment
• More effective palliation – high-tech palliation
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Long-term pain control
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Higher rates of complete pain response
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Prevention of metastatic spinal cord compression
ESTRO SBRT 2017 - Matthias Guckenberger
12
07.09.17