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ESTRO SBRT 2017 - Matthias Guckenberger

23

Patterns of failure after spine SBRT

Total

Failures

Adjacant

vertebra

Epidural Space Pedicles / posterior

elements

Ryu 2004

9 / 61

33%

Chang 2007

17 / 74

47%

17%

Gerszten 2007

6 / 51

0%

Nelson 2008

4 / 33

0%

50%

50%

Nguyen 2010

12 / 55

50%

33%

Conclusions:

• Safety of treating the involved vertebra only

• Areas at risk: epidural space and untreated parts of

vertebra

07.09.17

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ESTRO SBRT 2017 - Matthias Guckenberger

24

Target volume concept of RTOG 0631

Anatomical target volume concept:

• Inclusion of „volumes-at-risk“ in target volume

• Exclusion of tumors within 3mm distance to spinal cord

from practice of single fraction radiosurgery

07.09.17