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ESTRO SBRT 2017 - Matthias Guckenberger
23
Patterns of failure after spine SBRT
Total
Failures
Adjacant
vertebra
Epidural Space Pedicles / posterior
elements
Ryu 2004
9 / 61
33%
Chang 2007
17 / 74
47%
17%
Gerszten 2007
6 / 51
0%
Nelson 2008
4 / 33
0%
50%
50%
Nguyen 2010
12 / 55
50%
33%
Conclusions:
• Safety of treating the involved vertebra only
• Areas at risk: epidural space and untreated parts of
vertebra
07.09.17
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ESTRO SBRT 2017 - Matthias Guckenberger
24
Target volume concept of RTOG 0631
Anatomical target volume concept:
• Inclusion of „volumes-at-risk“ in target volume
• Exclusion of tumors within 3mm distance to spinal cord
from practice of single fraction radiosurgery
07.09.17