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RT changes the diversity of T-cell receptors
Demaria et al. Front Oncol 2012; 2: 1-7
Depletion of Treg (T cells which
modulate the immune system,
maintain tolerance to self-antigens,
and abrogate autoimmune disease)
Activation of antigen presenting
dendritic cells
Activation of cytotoxic T-cells (CD8
+
)
Altered expression of MHC-I and II