Framebased-Frameless_DV_2017_final.pptx

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Abscopal immune response

3 x 9.5 Gy

Postow et al:

NEJM 2012;366:925

Ipilumimab is an antibody aginst the T-cell CLTA4 receptor.

Inhibits the negative feed-back of cytotoxic T-lymphocytes