Framebased-Frameless_DV_2017

30%

Responders:

NSCLC: 4/18 (2 CR)

Breast: 5/14

Thymic: 2/2

Abscopal response

In 11/41 pts (27%)

GM-CSF: A potent stimulator of dendritic cell maturation

Abscopal effects with GM-CSF

Phase I data

Patients with stable or progressing metastatic solid tumours, on single-agent

chemotherapy or hormonal therapy, with at least three distinct measurable

sites of disease

35 Gy/10 frx

Golden et al. Lancet Oncol 2015; 16: 795