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Discussion: Clinical Relevance
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Should we measure intra-fraction motion?
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Yes, at planning in order to individualize the safety margin
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And if necessary to reduce the motion amplitude with compression
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Should we correct for intra-fraction motion?
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The penumbra is more sharp in abdomen than in lung
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Amplitude has an effect on the margin
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Still systematic uncertainties dominate the required margin
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Should we correct for inter-fraction motion?
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YES!
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Should we adapt the treatment plan?
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First solve issues mentioned above