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S944

ESTRO 36

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planning of AVM’s. This negates the need to perform an

invasive localised DSA in the majority of cases thereby

reducing risks associated with this procedure.

EP-1720 Framework for Statistical Cone-Beam CT

Reconstruction with Prior Monte-Carlo Scatter

Estimation

J. Mason

1

, M. Davies

1

, W. Nailon

2

1

University of Edinburgh, Institute for Digital

Communications, Edinburgh, United Kingdom

2

Oncology Physics Department, Edinburgh Cancer Centre,

Edinburgh, United Kingdom

Purpose or Objective

Scatter from the patient and detector leads to significant

inaccuracies and artefacts in cone-beam computed

(CBCT). Monte-Carlo (MC) methods may allow the scatter

signal to be accurately estimated based on a prior scan,

but this must be matched and calculated for the new cone-

beam measurements, and incorporated appropriately into

a reconstruction method. We investigate a framework for

statistical reconstruction with these prior MC estimates,

under various work-flows.

Material and Methods

The framework consists of statistical iterative

reconstruction with knowledge of a MC scatter estimate

from the planning CT. The estimate can be generated with

the scheme proposed by Xu et al. (PMB 2015) with online

registration and approximate MC of the prior, or by

calculating an accurate scatter off-line and warping to

match the new measurements, which will be faster. We

supplement the reconstruction with regularisation

spatially and between the prior image, hereby utilising the

planning image twice.

Results

The method was applied to data from repeat CT scanning

of a neck cancer patient, with a low-dose repeat CBCT to

form the new measurements. The figure shows

reconstructions from the framework along with

alternative approaches for comparison. The norm of the

error in attenuation coefficient through the region

containing the specimen is: 2.94 for

no scatter estimate

FDK

, which has no scatter correction; 1.74 for

uniform

estimate statistical

, which is statistical reconstruction

with a simple scatter estimate; 2.41 for

proposed estimate

FDK,

with prior scatter estimation; and 0.835 for

proposed

estimate statistical

, which is the proposed framework

combining double regularised statistical reconstruction

with prior scatter estimation. We note that using the

estimation strategy of Xu et al. in our framework yields an

error of 0.792.

Conclusion

We show that the general framework of statistical

reconstruction with prior scatter estimation is accurate

under low-dose acquisitions. The choice of our off-line

scatter estimation or the on-line approximate estimate of

Xu et al. is a trade-off in computational time and added

accuracy, but either perform well. We suggest this

quantitatively accurate method should be suitable for

adaptive radiotherapy, and we are planning further

testing with more applicable data.

EP-1721 A new calibration method of an Elekta XVI

(R.5.0.2) system able to achieve superior image quality.

D. Oborska-Kumaszynska

1

1

Royal Wolverhampton NHS Trust, MPCE Department,

Wolverhampton, United Kingdom

Purpose or Objective

During acceptance testing of an Elekta XVI system, it is

standard practice to only test system performance using

SFOV. The focus of this work was to develop and introduce

an extended customer acceptance test (AT) procedure as

a foundation for introducing a new calibration method of

an Elekta XVI (R.5.0.2) system. With optimal image quality

achieved for all FOVs during AT, more appropriate

optimisation of clinical XVI protocols can then be

performed.

Material and Methods

Following a significant service of the system (X-ray tube

replacement and calibration of the detector SDD), it was

first calibrated in line with the standard manufacturer

procedure. Extended ATs were then performed for all

FOVs. A CATPHAN 600 phantom was used to assess spatial

resolution, uniformity, contrast and geometry. The

parameters used by the reconstruction algorithm can

change depending on which AT you are performing (e.g.

spatial resolution, uniformity or contrast). It was

therefore necessary to assess all combinations of FOVs and

each test (e.g. MFOV with spatial resolution, LFOV with

uniformity…).

Results

The performed ATs showed unacceptable image quality

for MFOV and LFOV. Spatial resolution tests revealed

images with significant artefacts (Fig.1). The contrast

results were worse than 3%. The uniformity test results

were worse than 5%. The calibration procedure of the

system was repeated a few times but results were still

unacceptable. Investigations pointed to a few reasons:

very rigid reconstruction algorithm (FDK) with regards to

geometry, an exactly defined geometrical relation

between X-ray source (focal spot position) and the

coordinate system of pixels of the detector for each FOV,

and correction of flexmap offset required for each FOV.

This led to additional steps in the XVI system calibration:

X-ray beam axis alignment perpendicular to the imaging

panel surface and to “the centre” of that panel for each

FOV; calibration of lateral panel position and re-setting of

pots readings; re-calibration of flexmaps, badpixel maps

and gains of the imaging panel. The spatial resolution test

results showed for SFOV=13 lp/cm, MFOV=12.5 lp/cm,

LFOV=13 lp/cm and clear visibility of the spatial pattern.

The results for contrast were 1.85%; 2.39%; 2.91%,

respectively and for uniformity were 0.52%; 2.00%; 3.64%,

respectively.

Conclusion

Introducing extended AT for the Elekta XVI (R.5.0.2)

system provides full evaluation of the system before

introducing it in to clinical practice and ensures that

image quality is acceptable for all FOVs. The new

calibration procedure was able to realise the full and

proper reconstruction of image information and resulted

in a significant improvement of image quality for all FOVs,

as assessed by the above parameters.