Flipping Book - ATP

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Choosing an Algorithm
 Know the limitations of the surrogate/feature
 As distance from surrogate ↑, uncertainty increases ↑
 Variability localization/delineation = uncertainty
 These feed into PTV margins!
 Be skeptical: Are automated algorithms helping
 Are you closer to the desired clinical result?
 Is manual matching always required after automated?
 Magnitude? Do you need small or large adjustments?
 No? Review goals of registration vs. underlying metric
Practical Considerations