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Breast fibrosis – Increased risk of

Risk is increased:

Higher RT dose

RT boost on tumor bed

Postoperative breast oedema or hematoma

Seroma in tumor bed

Fibrosis, fat necrosis, hyperpigmentation

Bartelink Lancet Oncol 2015, Collette Eur J Cancer 2008, Mukesh Radiother Oncol 2012