287 / 1195
Regional radiotherapy instead of axillary surgery
AMAROS trial (EORTC): Radiotherapy or Surgery of the axilla
Donkers et al. Lancet Oncol 2015
•
4,806 BC patients (cN0)
sentinel node procedure
•
Tumorpositive sentinel node(s):
Axillary RT (n=681)
vs.
ALND (n=744)
Median follow-up 6.1 years:
Regional recurrence rate at 5 years: 0.54% ALND vs. 1.03% ART (NS)
Toxicity i.e. arm oedema at 5 years: 23% ALND vs. 11% ART
Clinical practice: Increased use of regional RT
Donker Lancet Oncol 2014