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Perfusion weighted images - PWI
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Rationale
Brain perfusion represents the steady state blood delivery
(i.e. nutrients and oxygen) through capillary bed
(GM= 60 ml/100g/min)
Post-contrast enhancement on T1-WI depicts only
disruption/absence of BBB
PWI (P-CT) can truly assess brain perfusion and relies on
“central volume theory”, depending on multiple factors and
reflecting the capillary density/richness
Courtesy of C. Colosimo. Inst. of Radiology/Neuroradiology.