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Perfusion weighted images - PWI
•
Rationale
The most accepted method is based on the so-called
Dynamic Susceptibility Contrast Technique (
DSCT
)
DSCT is performed by bolus injection of Gd chelate,
assessing the first pass of CM through the brain, but
obtaining also data regarding permeability (“leakage”)
CM must be injected at 5-6 ml/sec rate in order to obtain a
compact bolus and generate valuable
color maps
of
cerebral blood volume (
CBV
), time to peak (
TTP
), mean
transit time (
MTT
) and
CBF
(cerebral blood flow = CBV/MTT)
Courtesy of C. Colosimo. Inst. of Radiology/Neuroradiology.