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Number of CT Measurements (k)

1

2

3

4

5

6

7

8

9 10

Max Dose Reduction in CTV (% of Rx Dose)

0

2

4

6

8

10

12

14

16

18

20

22

24

26

28

30

32

34

36

38

Error bars: mean + 1 sd

80% of patients (

p

= 0.08)

95% of patients (

p

= 0.1)

Accumulating Dose with Organ Motion Deformation

• 2% maximum dose reduction:

•initial CT plus 4 suffices for 80% of patients (

p

=0.08)

4-field box

CTV = prostate+SV

similar result for prostate

only