911 / 1195
More General ART Strategies
Patient-specific PTV
Constructed with repeated
imaging.
Based on the first few days of
treatment.
Adapt the plan once using
MLC beam apertures to
correct margins and
systematic error.
No on-line interventions.
Reconstruct & Adapt Dose
Imaging feedback to assess dose in
moving and deforming organs.
“
4D
”
patient models.
Relate target/organ segmentations
Track deforming organs
Accumulate fraction doses
Evaluate dose delivered: to date,
current fraction, anticipated
“
trajectory
”
.
Yan et al PMB 42 (1997) 123–132
D.Yan, D. Lockman et al, IJROBP 48, 289–302, 2000
Martinez, Yan et al IJROBP 50, 1226–1234, 2001
D. Brabbins et al, IJROBP 61. 400–408, 2005
Nuver et al IJROBP 67(5); 1559-67 (2007)
Hugo et al Radioth & Oncol 78 (2006) 326–331
J Löf et al, PMB 43 (1998) 1605–1628
Birkner M et al, Med Phys. 2003 30(10):2822-31
Rehbinder et al, Med Phys. 2004 31(12):3363-71