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Adaptive Radiation Therapy Concept

Origins are informatics and modern control theory.

IGRT provides

feedback

, statistical treatment

deviations are observed.

Use knowledge to predict and address anatomical

(and biological) variation over time.

Imperfect feedback is a significant challenge.

Unpredictable variations leads to:

Incorrect interventions.

Efforts to over-control the process.

A need for robust decision support.

Yan et al., Sem. Rad. Oncol 20(2) 79-83 ( 2010)