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How to delineate the GTV (FDG-PET)
1. Manual:
•
Simple
BUT
•
Time
•
Window-level settings
•
Inter- and intra-observer variability
•
MD specialty and experience
2. Autosegmentation:
•
Threshold-based (converting PET image voxels into SUV): simple and
efficient
BUT
•
SUV cut-off values
•
Partial volume effect, tumor heterogeneity, motion artefacts
Zaidi & Naqa.
Eur J Nucl Med Mol Imaging
:2010;37:2165-87.