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6)

CTV DELINEATION FOR

3D-BRACHYTHERAPY

GTV-T

init

GTV-T

res

Macroscopic tumor extension at diagnosis

, proven by histology as

detected by clinical examination (GTV-T

clin

) and as visualized as a high-signal

intensity mass using T2-weighted MRI (GTV-T

MRI

).

Remaining tumor at the time of brachytherapy application

, determined

using the same clinical or imaging investigations, after treatment assumed

sufficient to control microscopic disease.

Can have undergone inflammatory reactions with edema and fibrotic remodeling (“

gray zones

”),

might or might not contain macroscopic or microscopic tumor.