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Including dose calculation uncertainty in DVH construction

• Uncertainty in a dose point has both type A

and type B uncertainty components

– (both for measured data)

• A probability density function can be used to

model uncertainty:

• Used Rectangular, Gaussian and Triangular

PTV

Utrecht 2016

distributions





 −

=

i

i

i

i

i

zD

f

f

σ

δ

δ

) (

) (

Prostate

Bladder

Rectum

Report uncertainty in DVH to enhance statistical treatment of

Clinical trial results?

Henriquez and Caastrillon MP 2010