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(
)
2
2
p
p
2.5 1.645
M
Σ
σ σ σ
= ⋅ + ⋅
+ −
”Exact” version of vHMF for 90% CDF(CTV) and 95% dose
0.1
0.2
0.3
0.4
(
)
2
2
1.645
0.32 0.32
σ
⋅
+ −
0.7
σ
⋅
Most common version
2.5 0.7 cm
M
Σ σ
= ⋅ + ⋅
0.1
0.2
0.3
0.4
0.5
Limitations?
•
infinite number of fractions (convolution)
•
large box shaped PTV for the dose profile
(analytical convolution)
•
spherical shape of the CDF for the CTV
(analytical CDF)