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“considering CTV preparation

uncertainties so that for 90% of

the patients the entire CTV is

inside the ITV”

True, unknown

CTV

inside the true, unknown

ITV

“considering CTV preparation

uncertainties so that for 10% of

the patients some CTV is outside

the ITV”

How much is some?

8

10

probability for a patient to have some CTV outside of ITV

%

Captured

CTV

inside the captured

ITV

Due to symmetry, the probability of

the true, but unknown CTV

being inside the captured ITV

is equal to the probability of

the captured CTV

being inside the true, unknown ITV

0

2

4

6

8

10

0

2

4

6

CTV volume outside of ITV

probability

Σ

=0.05

R

Σ

=0.1

R

Σ

=0.2

R

%