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Chordoma Chondrosarcoma
03/01/13
CHORDOMA
0.84 per 1’000’000 (M>F)*
Median age 58 (3 - 95)
Intracranial chordomas invariably
involve the clivus
Those arising from :
(a) the most rostral notochordal
extension in the dorsum sellae present as
sellar/parasellar tumors
(b) the most ventral part of the clivus
present as
nasopharyngeal tumors
(c) those associated with body and dorsal
aspect of clivus manifest as
spheno-
occipital or petrosal lesions
(d) those related to the lower clivus will
present at the
ventral portion of the
foramen magnum
Direct dural invasion responsible for
extension to posterior fossa
CHONDROSARCOMA
•
5 per 1’000’000 (M>F)
•
Median age 51 (1 – 102)
•
Appendicular > axial > soft tissue
EPIDEMIOLOGY
* Incidence and relative survival o f chordomas: the standardized mortality ratio and the impact of chordomas on a p opulation .Smoll
NR, Gautschi OP, Radovanovic I, Schaller K,
Weber DC
.
Cancer. 2013 Jun 1;119(11):2029-37. doi: 10.1002/cncr.28032. Epub 2013
Mar 15