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Introduction (1)
•
Originate from
ependymal cells
lining the
ventricules and central canal
•
Classified according to the
WHO
classification
(i.e. grade 1*-2-3)
•
30%
of change of grading after centreal review
UKCCR/SIOP (50%/50%)
•
Can arise anywhere in the CNS but show a
preference for the
posterior fossa
(Children+++)
•
In older patients, ependymoma often arise
within the brain parenchyma
03/01/13