581 / 1266
Outcome (RT alone, chx – RT, chx. alone)
Radiotherapy in pure germinoma
Author
Pat.
Therapy
RFS (5 years)
Bamberg
1999
11
49
RT CSA 36 Gy+Tu 14 Gy
RT CSA 30 Gy+Tu 15 Gy
100%
88.8%
Bouffet, 1999
44
Chx. + RT tumour
98% (3 years)
Balmaceda, 1996
45
Chx. alone
50%
Haddock, 1997
48
12 RT CSA/tumour
11 RT whole brain/tumour
24 RT ventricular system
10 y. 94%
94%
0%
Kitamura, 1999
13
Chx. / RT tumour : 24 Gy
100%
Aoyama, 1998
41
23 RT CSA/tumour
10 RT whole brain / tumour
8 RT tumour
10 y. 90%
76%
22%
Hardenbergh, 1997
40
30 RT CSA/tumour
10 RT whole brain/tumour
100%
100%
Cefalo, 1995
7
Chx. / RT tumour region
5 relapses (ventricles)
Kellie, 2004
Da Silva 2010
11
25
Chx. alone
47%
6 y : 45.6% / OS 75.3%
Kortmann, 2001
155
102 RT CSA
53 other treatments
99.5% (CNS)
49% (CNS
)
Shikama, 2005
180
114 RT whole brain / Boost
8 y. EFS 89%, OS 91%