816 / 1266
Medulloblastoma- Randomised studies of CSI RT dose
POG 8631/CCG 932 (1986-1990)
- 23.4 Gy – 52 % 5 year EFS
- 36 Gy – 67 % 5 year EFS
- p 0,08 (trial stopped for an increased risk of
isolated neuraxis failure)
- 23.4 Gy – 52 % 8 year EFS
- 36 Gy – 60 % 8 year EFS
- p 0,141