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Dabrafenib Activity in Brain Metastases

Dabrafenib, at the

recommended phase 2 dose,

has activity against brain

metastases in adult patients

with melanoma

1

Nine of ten (90%) melanoma

patients with untreated brain

metastases showed reduction

in brain lesion size

1. Falchook GS,

et al

.

Lancet

2012;379:1893–1901.

105