997 / 1266
Phase I: Best Overall Tumor Response and
Correlation With 5-Gene Hh Signature in MB
Responders/Hh-
activated
Responders/Hh-
non-activated
Adults
3/3 (3 PR)
0/4
Children
2/2 (2 CR)
0/12
Total
5/5
0/16
CR, complete response; Hh, hedgehog; MB, medulloblastoma; PR, partial response
Amakye D, et al. AACR 2012. Abstract #4818.