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ESTRO IG and Adaptive Course

Parikh Budapest 2018

Dose escalation may improve SURVIVAL in

Pancreatic Cancer

Retrospective report from

MD Anderson

Tumors at least 1 cm from

a GI structure (25% of

patients) were

considered for

hypofractionated dose

escalation

Patients who received

radiotherapy with BED

> 70 Gy had an

improved overall

survival of 36% versus

19% at 2 years, and 31%

versus 9% at 3 years

Krishnan et

al, IJROBP,

Moningi et al,

Ann Surg