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Dose constraints

Current dose constraints based on non-

adaptive plans (ie 45-50 Gy to 0.5cc dose to GI

structures in hypofractionated regimen; 33-36

Gy to 0.5cc dose to proximal GI structures in

SBRT regimen)

These are not cumulative doses because we

don’t have technology to measure this

We don’t know what the real tolerance is!