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62

patients with

pT2-T4a N0 M0

bladder

carcinoma unsuitable for standard daily

radiotherapy

RANDOMISE

1:1

Due to receive six 6Gy fractions of

radiotherapy delivered weekly

(total dose: 36Gy over 6 weeks)

National Trial

Group 1:

STANDARD PLANNING

(CONTROL)

Group 2:

ADAPTIVE PLANNING

(EXPERIMENTAL)

Follow up

Weekly on treatment

4 weeks after last treatment

3 months after last treatment

6, 12 and 24 months

in partnership with