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Page Background

Primary endpoint

Acute non-genitourinary grade 3 or greater toxicity (up to 3 months

following treatment completion)

Secondary endpoints

Local disease control rate at 3 months

Control rate of presenting symptoms

Endpoints

Patient reported outcomes

Late toxicity

Time to local disease progression

Overall survival

Proportion of fractions benefiting from adaptive planning

Appropriate identification and correction of fractions requiring

adaptive planning

in partnership with