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Alternative : robust prescription

PET dilated deblurred

9%

Heterogeneous

*prescrip.on

*

D

P

D

P Dilated

Robust

*prescrip.on

*

D

RP

D

Planned

QVH

!

(

Q

0.95

)

planning

>95%22

(

Q

1.05

)

planning

<5%22

*

QVH

!

(

Q

0.95

)

α

Σ,σ

2

>95%22

for2all2direc;ons22

Yes2

Treat

!

Displacements2by222

Blurring2by2222

Dila;on2by22

Deblurring2using2

Planning2

α

Σ

σ

σ

α

Σ

!

!"#$$%&

(! ± !!) ⊗ !(!, !)

!

Yes2

1%

2%

3%

Spherical%tumor%

−3

−2

−1

0

1

2

3

70

72

74

76

78

80

82

84

86

88

90

Position from center of tumor (cm)

Dose (Gy)

Profiles acquired through center of tumor

Original prescription

Dilated prescription

Robust prescription

GTV

PTV

Court. of E.Sterpin,

Only dependent on

σ

and

Σ

independant of TPS