

Alternative : robust prescription
PET dilated deblurred
9%
Heterogeneous
*prescrip.on*
D
P
D
P Dilated
Robust
*prescrip.on*
D
RP
D
Planned
QVH
!
(
Q
0.95
)
planning
>95%22
(
Q
1.05
)
planning
<5%22
*
QVH
!
(
Q
0.95
)
(±
α
Σ,σ
2
>95%22
for2all2direc;ons22
Yes2
Treat
!
Displacements2by222
Blurring2by2222
Dila;on2by22
Deblurring2using2
Planning2
α
Σ
σ
σ
α
Σ
!
!"#$$%&
(! ± !!) ⊗ !(!, !)
!
Yes2
1%
2%
3%
Spherical%tumor%
−3
−2
−1
0
1
2
3
70
72
74
76
78
80
82
84
86
88
90
Position from center of tumor (cm)
Dose (Gy)
Profiles acquired through center of tumor
Original prescription
Dilated prescription
Robust prescription
GTV
PTV
Court. of E.Sterpin,
Only dependent on
σ
and
Σ
independant of TPS