3-years GU (G2-3) toxicities correlated with both high and
“low” dose if empty bladder
(
Harsolia, IJROBP, 2007)
V30Gy < 33.5 cc 2% G3
V30Gy > 33.5 cc 20% G3
V82Gy < 2.5 cc 2% G3
V82Gy > 2.5 cc 12% G3
8 years GU (G1-3) toxicities correlated with “
hottest volume
”
V78Gy < 2.9 % 25 % 8-years risk
V78Gy > 2.9 % 50 % 8-years risk