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Schwartz

IJROBP 2005

“Dose heterogeneity is an option to further

escalate the dose in the target rather than a

price to pay for using IMRT”

Dose escalation 3D vs IMRT: 6% vs 17-35%

Grills

IJROBP 2003

Dose escalation: IMRT>>25-30%

St Hilare

Radiot Oncol 2009

Dose escalation: >78 Gy in 5/7 cases

3D vs IMRT: PTV Dose escalation in the target”