1521 / 1544
Murshed
IJROBP
2004
41 pts
Stage IIIA-IIIB
PTV:
623cc (75-1645)
Upper location
V10: 45 vs 38 (p<0.01)
(
IMRT benefit 7-
10%
)
V20: 35 vs 25 (p<0.01)
(IMRT benefit 7-
10%)
MLD 19 vs 17 Gy
NTCP: 36 vs 9% (Burman);13 vs 7%
(Hyman)
Grills
IJROBP
2003
Node -
Node +
V20: 25.6 vs 23.6%
36.3 vs 23.6%
(
IMRT benefit ≈
15%
)
MLD: 15.3 vs 15.4 Gy
21.5 vs 15.4
Liu
IJROBP
2004
Stage I-IIIB
10 pts
V10: IMRT benefit 1.6%
V20: IMRT benefit 8%
V30: IMRT benefit 8.9%
3D vs IMRT: LUNG