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ESTRO IMRT course 2015
IMRT optimization: algorithms&cost functions
Brussels October 5th, 2015
-50-
Dose
Regret
The
regret
grows quadratically
with the violation
of the required/
tolerated dose
)
( )
( 1
0
1
2
0
i
N
i
i
underdose
DD DD
N
F
−
−
=
∑
=
θ
)
( )
( 1
0
1
2
0
DD DD
N
F
i
N
i
i
overdose
−
−
=
∑
=
θ
D
0
The most Common Physical Cost Function:
One-Sided Quadratic Penalties