

ESTRO IMRT course 2015
IMRT optimization: algorithms&cost functions
Brussels October 5th, 2015
-52-
25 Gy
Dummy
volume around
target for gradient
Local Control of a Quadratic Overdose Penalty
red
/
yellow
voxels:
highest contribution to
the cost fuction (CF) ,
i.e. in these voxels the
CF puts most ‘pressure’
to the optimizer to
reduce dose
example:
quadratic overdose
penalty for D
0
=25Gy,
i.e. area of control
only at doses > 25 Gy