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ESTRO IMRT course 2015
Adaptive Radiotherapy
Brussels October 8th, 2015
-32-
This was all offline ART…
Now: Online Adaptive Re-Planning
IMRT
plan
CT
Fx
1
no margin!
IMRT
plan
CT
Fx
2
IMRT
plan
CT
Fx
N
…
M. Ghilezan et al. (2004): Online image-guided intensity-modulated
radiotherapy for prostate cancer: How much improvement can we expect? A
theoretical assessment of clinical benefits and potential dose escalation by
improving precision and accuracy of radiation therapy. IJRPBP 60(5)
Idealized assumptions to investigate a ‘gold-standard’ benchmark online ART
scheme:
•
daily pre-treatment imaging and online IMRT replanning
•
no intrafractional or other uncertainties => no PTV-margin necessary
•
evaluation using deformable dose accumulation of multiple CTs of 18 patients