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ESTRO IMRT course 2015
Adaptive Radiotherapy
Brussels October 8th, 2015
-33-
This was all offline ART…
Now: Online Adaptive Re-Planning
IMRT
plan
CT
Fx
1
no margin!
IMRT
plan
CT
Fx
2
IMRT
plan
CT
Fx
N
…
Results (in short):
• average dose escalation by 13% possible, but with large interpatient
variation (5-41%).
• 27% of the patient would have only minimal benefit (<5% dose
escalation), 32% would have significant benefit (>15% dose esc.)
Ghilezan et al. 2004
(IJROBP 60(5))
Note!:
•
comparison relative to non adaptive standard IMRT (1 cm margin),
not to offline adaptive IMRT.
•
no margin, intrafraction motion and all other uncertainties neglected