

ESTRO IMRT course 2015
Adaptive Radiotherapy
Brussels October 8th, 2015
-41-
Treatment of targets with large interfractional
deformations: Plan-selection strategies
•
ART for bladder cancer, online adaptive 3-plan library:
compared to non-ART,
V
57Gy
of body tissue reduced by 34%
(Vestergaard et al. 2013, Rad. Onc. 109(3))
and
median PTV volume reduction by 30%
(Vestergaard et al. 2014, Acta Oncol.
accepted
)
Bondar et al. 2011 (Rad. Onc. 99(2)); courtesy M. Hoogeman (Erasmus MC)
•
ART for cervical cancer: For 90% of pts. with CTV coverage of >=95%…
* non-ART population based
CTV-PTV volume 1702
±
274ml
(38mm margin)
* online-adaptive 2-plan library:
CTV-PTV volume 764
±
165ml
(7mm margin)
(Bondar et al. 2012, IJROBP 83(5))
Example:
female pelvis