588 / 1544
ESTRO IMRT course 2015
Adaptive Radiotherapy
Brussels October 8th, 2015
-45-
Biologically Adapted Radiotherapy
Å. Søvik et al. 2010
(Sem. Rad. Onc. 20(4))
•
adaptation by patient-individual
biological/functional feedback
•
tumor:
changes in perfusion, hypoxic
areas/re-oxigenation, tumor cell
metabolism
•
early predictive discrimination between
‘responders’ and ‘non-reponders’
•
normal tissues:
e.g. lung perfusion
changes, early detection of potential
radiation-induced toxicity